Douglas Labs Corvalen Ribose OPC 165 Grams
DESCRIPTION Corvalen® OPC is all natural D-ribose for energy support combined with potent antioxidants including oligomeric proanthocyanidins (OPCs). OPCs are some of the most powerful antioxidants to help neutralize free radicals and support healthy aging.
FUNCTIONS Corvalen® contains pure D-ribose, a safe and clinically researched ingredient that supports the natural way our bodies produce adenosine triphosphate (ATP), the energy currency of the cell. † Ribose is the vital structural backbone of critical cellular compounds called purines and pyrimidines. Our bodies must have an adequate supply of purines and pyrimidines to form major cellular constituents such as our genetic material (DNA and RNA), numerous cofactors, certain vitamins, and, importantly, adenosine triphosphate (ATP). Ribose is the starting point for the synthesis of these fundamental cellular compounds, and the availability of ribose determines the rate at which they can be made by our cells and tissues.
D-ribose is a structural component of DNA, RNA, ATP, GTP, flavins (FAD, riboflavin) and other important nucleotides found in all living cells. Ribose is formed naturally via the pentose phosphate pathway. This pathway is slow and rate-limited in cardiac and skeletal muscle due to an inherently low concentration (lack of expression) of the enzymes, glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase. The product of this pathway is ribose-5-phosphate, which in turn is converted to 5-phosphoribosyl-1- pyrophosphate (PRPP), the primary driver in the synthesis and salvage of purine nucleotides. No other compound can be used by the body for this metabolic purpose. Purine nucleotides (ATP and its precursors) lost due to ischemia, hypoxia, or genetic predisposition is replaced via the purine nucleotide pathway. This pathway is rate limited by the availability of ribose in tissue. Administration of exogenous ribose bypasses the rate-limiting steps in the pentose phosphate pathway, resulting in a significant acceleration of PRPP. Renewed concentration of ATP is accompanied by an increased energy potential in the cell, also known as the “energy charge.” Cardiac and skeletal muscle functions (i.e. contraction, cell wall maintenance, relaxation, polarization of the cell membrane) each require a different, quantifiable energy charge to drive or provide allosteric regulation for each function. Restoration of cellular energy charge restores function consistent with the degree of energy charge restored.
INDICATIONS Corvalen® OPC is an all-natural D-ribose supplement with organic pomegranate and OPC antioxidants to help restore energy, support cardiac function, fatigue, and healthy aging.
SUGGESTED USE Take 1 scoop one to two times daily, taken with or near a meal. A third serving may be added with a mid-day meal as needed. Dissolve powder in 2 oz. or more of water or juice. Do not mix with carbonated beverages.