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Omega-6 fatty acids are well-supplied in the diet by meat and vegetable oils. However, not all omega-6 fatty acids are of equal value.
Arachidonic acid (AA) tends to be unhealthy because it is the precursor of inflammatory eicosanoids — such as prostaglandin E2 (PGE2), thromboxane A2, and leukotriene B4 — which promote inflammation.
In contrast, gamma-linolenic acid (GLA), found in evening primrose oil, borage oil, and black currant oil, is an important fatty acid that plays a beneficial role in healthy prostaglandin (PGE1) formation and pro-inflammatory mediator reduction.
Health-conscious people have been swallowing a lot of borage oil supplements to obtain GLA (gamma linolenic acid), the parent of the biologically active DGLA (dihomogamma linolenic acid).
Life Extension adds 10 mg of sesame lignans to each softgel of Mega GLA borage oil. Sesame lignans not only increase beneficial DGLA but they also prevent the conversion of GLA into the proinflammatory mediator arachidonic acid.
Blocking this pathway decreases the formation of destructive proinflammatory agents prostaglandin E2 and leukotriene B4.
Numerous studies document GLA’s multiple health effects. Enhancing this supplement with sesame lignans enables GLA to work much better in the body, allowing many more people with inflammatory-related problems to benefit from supplemental GLA.
Life Extension's mission is simply to help you live a healthier, longer life. They are at the forefront of medical research, constantly looking for ways to prolong youth, health, and life. They have been at it for more than 34 years, investing more than $140 million to find therapies and technologies that could lead to lifesaving cures for the diseases of aging.
Life Extension insists on purchasing only the highest quality raw materials from all over the world, primarily from leading US, Japanese and European sources. They go one step further by using advanced analytical methods, such as high-performance liquid chromatography and gas chromatography/mass spectrometry, to ensure Their products meet label claims for potency and purity. Life Extension tests its raw materials using US Pharmacopeia and other exacting pharmaceutical assay standard.
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