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Item #: AANEP300
Reg. Price: $199.99
Our Price: $144.99

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Neprinol- 300 caps (price includes free shipping)


Neprinol Supports:


  • Normal Immune Function

  • Normal Blood Clotting

  • Blood Cleansing

  • Viral Cleansing

  • Fibrinolytic Activity

  • Normal Blood Viscisity

  • Circulatory Health

  • Normal Blood Pressure

  • CRP (inflammatory markers)


NEPRINOL is composed of Pharmaceutical-grade ingredients, provided exclusively through licensed healthcare practitioners and supplementation outlet stores. NEPRINOL  is 100% natural and contains no animal derivatives, available now without a prescription.


Fibrin is a particular substance formed in the human body that plays a role in a host of health conditions.  Fibrin is responsible for scar tissue, thrombus formation, arthritic and inflammatory conditions along with associated pain.

Neprinol-AFD by Arthur Andrew Medical is designed to address fibrin in the body.  Removal of fibrin by the body is accomplished by enzymes (principally plasmin) whose role is to attack the excess fibrin buildup.  Neprinol-AFD provides superior fibrin-active enzymes in a combination designed to address fibrin buildup and more.


NEPRINOL is radically more advanced than today's leading systemic enzyme blends. NEPRINOL's formulation is more complete and essential than a daily vitamin. Replace the enzymes that Mother Nature takes away from us as we age.

NEPRINOL contains several sources of anti-oxidant rich ingredients, as well as a full spectrum of proteolytic (protein digesting) enzymes, enterically coated to adapt to a wide spectrum of pH levels.

NEPRINOL's exclusive formulation contains several highly concentrated digestive enzymes that enable the body to digest fats, proteins, sugars, and carbohydrates.  These digestive enzymes are designed to work in the blood removing waste material and converting undigested food particles into energy.

Enzyme Deficiencies May Lead To:

Angina High Blood Pressure
Acid Reflux Disease High Cholesterol
Antibiotic Infection Hypercoagulation
Anti-Inflammatory - Anti-Endemic Hypertension
Antioxidant Increased Risk of Stroke
Arthritis Intermittent Claudication
Atherosclerosis Multiple Sclerosis
Chronic Fatigue "CFS" Ocular Degeneration
Chronic Pain Peripheral Neuropathy
Diabetes Type II / Risk Peyronie's Disease
Digestion Phlebitis / Thrombophlebitis
Endometriosis Polycythemia Vera
Fibrocystic Breast Disease Retinopathy
Fibromyalgia Syndrome Rheumatoid Arthritis
Glomerulonephritis Uterine Fibroids


Dr. Recommended NEPRINOL AFD:

NEPRINOL AFD is the most scientifically advanced broad spectrum enzyme blend available. NEPRINOL AFD uses individually enterically coated enzymes to increase pH range and resistance to stomach acid.

NEPRINOL AFD is the first systemic blend with 100% pharmaceutical grade components and the purest form of Serrapeptase, Nattokinase and Co-Q10 available. Several years of scientific research and clinical studies have been conducted on each and every component that makes up NEPRINOL AFD. For the first time ever, you can get all of these enzymes in one powerful product.

Fibrinolytic enzymes such as Nattokinase and Serrapeptase can substantially lower C - reactive protein levels (CRP),an inflammation marker linked to heart attack.  A clinical trial involving 18,000 healthy patients with normal cholesterol, found that elevated levels of CRP were associated with a threefold increase in the risk of heart attack.  Unlike taking daily aspirin, NEPRINOL AFD thins the blood by removing unwanted debris.

NEPRINOL AFD does not generate gastrointestinal distress, and does not put stress on the liver. For those already affected by heart disease, fibrinolytic enzymes have shown the ability to emulsify arterial plaque, remove scar tissue, and lower LDL cholesterol. Nattokinase has been clinically shown to remove arterial blockages 60% faster than the body's natural fibrinolytic enzyme plasmin.  The combinationof Serrapeptase and Nattokinase in Neprinol AFD offers this complete fibrinolytic compliment of enzymes.


How to choose an enzyme blend:

Not all enzyme blends are created equal. There are only a handful of enzyme formulations that actually work. The formulators of NEPRINOL AFD have created some of the finest enzyme products available.  You should know that enzyme potency is measured by activity levels.

When enzymes are added to liquid they become active. Simply adding more mg of enzymes does not necessarily make the product stronger.  Activity levels are measured by "FU's" or fibrinolytic units. With most enzyme blends, typical serving size is 1-2 capsules, providing an average of 1,000 - 2,000 FU's. NEPRINOL AFD provides 15,000 FU's per serving, yielding 133% higher activity levels. When choosing an enzyme look carefully for FU's rather than mg per serving.

NEPRINOL AFD taking enzymes to a new level:

NEPRINOL AFD contains the three main ingredients that you need to reinforce your body's own enzymes. These enzymes are essential for a host of health support issues including inflammatory response. Serrapeptase breaks down fibrin within the body and helps modulate the immune system, Nattokinase improves cardio-vascular health and helps address arterial plaque formation. Finally Co-Q10 is regarded as one of the most potent antioxidants available.  Co-Q10 helps fight free radicals.



Why do I need enzymes?

As we age, enzyme production is radically diminished. These enzymes are needed to maintain a healthy immune system, healthy joints, good circulation and overall balanced reaction to injury. The older we get our need for enzyme production increases while the amount of usable enzymes in our body is gradually depleted. Enzyme deficiency can lead to wide variety of health problems. NEPRINOLAFD contains 100% vegetable derived enzymes.

These enzymes are biochemically more effective than our bodies own natural enzymes. Supplementation with NEPRINOL AFD along with proper diet and exercise can greatly reduce vulnerability to a wide range of health concerns.


What are "systemic" enzymes?

Systemic enzymes differ greatly from digestive enzymes that do most of their work in the stomach and intestine. NEPRINOL AFD provides individually enterically coated enzymes. Enterically coated enzymes pass safely through the stomach and digestive tract and are quickly absorbed into the bloodstream in their natural state. Enzymes are completely universal, in that they react differently depending on how they are introduced to the body.

Enteric coating allows these enzymes to work systemically or throughout the entire body. NEPRINOL AFD uses a highly advanced delivery system that ensures delivery of the enzymes to all of your tissue and organs in their most active state.


How does NEPRINOL AFD work?

NEPRINOL AFD contains a blend of proteolytic or protein digesting enzymes. Some proteins can be harmful to joints, organs, tissue, and can increase our vulnerability to certain viruses. NEPRINOL AFD's blend of proteolytic enzymes can emulsify and break down these harmful proteins.



It's remarkable that one product can provide benefit for so many different conditions. By supplementing and replenishing the body's enzymes NEPRINOL AFD provides one of our most essential and basic biochemical needs. NEPRINOL AFD has been used by people suffering from: arthritis, joint problems, poor circulation, weak immune systems, sports and work injuries, and much more.



No serious or adverse side effects have been reported from taking systemic enzymes such as NEPRINOL AFD. Clinical studies have shown that even extremely large doses of these enzymes are not toxic. If you are taking blood-thinning medication, you should consult with your physician before taking NEPRINOL AFD.


NEPRINOL AFD is a proprietary combination of Nattokinase, Serratiopeptidase, Rutin, Alma and other proteolytic enzymes specially formulated to assist your body's defense of the damaging effects of fibrin.  As fibrin builds up in our bodies, it can cause many unhealthy conditions.  NEPRINOL AFD can help reduce fibrin levels.  NEPRINOL AFD can be used with other dietary supplements.


Warning: Do not take NEPRINOL without the consent of your physician if you are currently taking anti-coagulants or you are pregnant or lactating (as these subjects have not yet been tested) 


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Side Effects - Enzymatic Detoxification

NEPRINOLAFD is the most potent systemic enzyme blend available.  These enzymes use a lock and key mechanism to emulsify and release dead, dying and toxic materials from the body.  When this process takes place the only way to cleanse the body is to release this debris back into the bloodstream so that it may be processed by the liver and kidneys and then finally released through urination or a bowel movement. 

We refer to this process as Enzymatic Detoxification, which can sometimes be uncomfortable. Symptoms such as headache, fatigue, upset stomach and diarrhea may occur.   If at any point you may start to feel ill you may be detoxifying too quickly.  Decreasing your dosage for a more gradual and comfortable detoxification period is therefore recommended.  It may take several days to completely cleanse the body of unwanted debris.

We recommend drinking plenty of water during detoxification to allow the body to dilute the toxins that are being expelled.  Please call us anytime if you begin to feel ill.


Enzymatic Detoxification is only temporary and in some of the most extreme cases will not last for more than a period of 14 days.   Please use the dosing schedule below as a reference for taking NEPRINOLAFD. 


NEPRINOL is a proprietary combination of Nattokinase, Serratiopeptidase, rutin, alma and other proteolytic enzymes specially formulated to assist and defend your body from the damaging effects of fibrin.  As fibrin builds up in our bodies, it may cause many unhealthy conditions. NEPRINOL can help keep fibrin and its harmful results under control. NEPRINOL can be used with other dietary supplements.


SUGGESTED USE: As a dietary supplement, take one or two capsules three times a day, in between meals with 8oz. of water.


WARNING: Do not take NEPRINOLwithout the consent of your physician if you are currently taking anti-coagulants or you are pregnant or lactating (as these subjects have not yet been tested) 



Serving Size: One Capsule 15,000 FU (500mg)



Amount Per Serving

% Daily Value

Neprinol Blend: 500mg

SEBkinase Systemic and Lipolytic Enzyme Blend:

(NattoSEB (USP Grade Nattokinase),

Peptizyme SP (USP Grade Serratiopeptidase), Lipase)


Neprinol Protease Blend:

(Microbial proteases derived

From (A. oryzae, B. subtilis and Serratia))


Neprinol Enzyme and Cofactor Blend:

(Amla, Papain, Bromelain, Rutin, Ubiquinone

(USP Grade Coenzyme Q10))












*Daily Value not  established



Other ingredients: Maltodextrin, Cellulose (capsule)


Company History


Arthur Andrew Medical was established in 2003 by Justin Marsh after successfully selling and marketing enzyme products with his former distribution company.

Through his experience working with the enzyme and probiotic products available at the time, Mr. Marsh saw an opportunity to bring higher quality and more efficacious products to his client base after developing relationships with several of the world’s largest enzyme producers. He felt that the small but vitally important niche of enzyme supplements was led by outdated and inferior products that had become popular simply due to their age within the market. Mr. Marsh also strove to lay the foundational values of his vision with those that he would expect with a product that he would provide to his own family.

To that end, Arthur Andrew began developing its first product with the collaboration of well-known enzymologists and utilizing best-in-class materials. Each material was only considered if it were well researched, had a proven record of safety, demonstrated efficacy, was vegan friendly, and only utilized non-GMO materials in the manufacturing process. With those criteria met, Arthur Andrew Medical began to create finished products under its own brand-name. In 2004, Neprinol, the world’s most potent non-animal derived systemic enzyme was born. As Neprinol flourished on the market, Mr. Marsh saw that many companies were developing products based on market fads, so he steered Arthur Andrew Medical towards innovation and science to ensure that the company maintained its position as an industry leader.

To this day, Arthur Andrew has grown to manufacture 11 products under its own brand and they continue on their mission of expanding their line with highly efficacious products that unlock the true potential of one's health.

Mission Statement

Arthur Andrew Medical aims to provide products of the highest quality and purity with the goal of unlocking the potential of one’s health. We strive to be at the forefront of creativity and innovation while maintaining a strong commitment to ensuring safe and reliable products. We endeavor to provide products that our clients recommend to their family and friends, that physicians prefer for their patients, and that our employees can be proud of.

Why are many Arthur Andrew products proprietary?

Posted September 29, 2015

Many may wonder why certain Arthur Andrew products are kept proprietary. Proprietary formulas have their pros and cons, and to a client's eyes may have more cons than pros. However, the main issue specific to enzymes is that they are not like vitamins that can simply be measured by weight. The weight to activity ratio can vary greatly from one enzyme's lot to its subsequent lot, let alone factoring in competing products and manufacturers. And since activities are used for enzymes, does anyone really know what 45,000 SPUs of serrapeptase or 1,000 GDUs of bromelain really means once its inside the body? The short answer is no, but if we are looking at individual enzyme products like our Serretia, it certainly can help one deduce which product is a better "buy." However, it is not necessarily an indication of what the product will do once consumed... only that it may be stronger than another product. This type of comparison becomes nearly impossible once you begin combining enzymes into formulations such as Neprinol. As far as how the enzymes behave in the body, we have put a lot of time and effort into formulating our products to provide specific health benefits, not specific amounts of any one enzyme or component. In our opinion, looking at any of our formulations from an enzyme to enzyme perspective is doing oneself a disservice. Neprinol for instance is formulated to be a blood cleanse, help support normal inflammatory levels, and provide dozens if not hundreds of other health benefits, not just supplement one's body with some arbitrary number of SPUs of serrapeptase. We ideally would like our formulations to be looked at as a whole, not in parts. The proprietary nature of our formulas is not to "hide" anything. It's meant to hopefully make the decision of choosing a product easier by simplifying what the product is and what it is intended to do. Rather than Neprinol being a combination of nattokinase, serrapeptase, protease and other components, we want it to be looked at as the "Neprinol formula." Hopefully this makes sense and can make everyone more comfortable with our highly efficacious line of products.



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