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Item #: LEFED
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Life Extension Endothelial Defense with Full-Spectrum Pomegranate, 60 Softgels


The vascular endothelium is the inner lining of blood vessels that regulates arterial and venous health. The reason for many circulatory problems is the breakdown of endothelial function and structure. Fortunately, there are nutrients that have been clinically shown to help maintain healthy endothelial function and arterial circulation.

Pomegranate promotes cardiovascular health:

In a group of aging humans with risk factors for cardiovascular events, pomegranate or a placebo was ingested daily. Both groups continued taking their conventional medications.

After twelve months, carotid artery conditions (measured as carotid intima-media thickness) were improved 30% in the pomegranate group while carotid artery conditions worsened by 9% in the placebo group.

Additionally, in those who consumed pomegranate, total antioxidant status was increased by 130% while blood serum levels of LDL basal oxidative state and LDL susceptibility to oxidation were both significantly reduced by 90% and 59% respectively.

In a similar study, pomegranate or a placebo was ingested daily. After only three months, coronary artery blood flow improved by 18% in the pomegranate group but worsened by 17% in the placebo group.

A next-generation pomegranate extract, blending standardized extracts from the whole fruit, flower and seed oil, is one of the active components of Endothelial Defense formula. Full-Spectrum Pomegranate provides this fruit’s unique polyphenols with newly discovered biologically active compounds from other parts of the pomegranate plant.

SOD protects against nitric oxide degradation:

Aging reduces the body’s production of a critical antioxidant called superoxide dismutase (SOD), which provides the body’s first enzymatic step in the defense system against oxidative stress. Diminished SOD levels are closely linked with increased vascular oxidative stress, which contributes to endothelial dysfunction.

An orally active superoxide dismutase (SOD) called GliSODin has been clinically shown to support healthy arterial function and structure, while boosting levels of the body’s most powerful antioxidant enzymes (SOD and catalase) and protecting against oxidative stress-induced cell death.

Studies show that carotid artery thickness detrimentally increases by 0.04 mm every ten years. However, a recent study with GliSODin suggests that 2.8 years of supplementation may turn back the clock on 10 years of age-related damage due to carotid artery wall thickening.

Endothelial Defense formula contains GliSODin in a dose identical to that which was used in this successful human study.

Endothelial Defense provides the best-documented nutrients to help you maintain healthy arterial blood flow and normal blood pressure.

Life Extension's mission is simply to help you live a healthier, longer life. They are at the forefront of medical research, constantly looking for ways to prolong youth, health, and life. They have been at it for more than 34 years, investing more than $140 million to find therapies and technologies that could lead to lifesaving cures for the diseases of aging.

Life Extension insists on purchasing only the highest quality raw materials from all over the world, primarily from leading US, Japanese and European sources. They go one step further by using advanced analytical methods, such as high-performance liquid chromatography and gas chromatography/mass spectrometry, to ensure Their products meet label claims for potency and purity. Life Extension tests its raw materials using US Pharmacopeia and other exacting pharmaceutical assay standard.


 

Supplement Facts:

Serving Size: 2 softgels

Servings Per Container: 30

Amount Per Serving:

Superoxide Dismutase/Gliadin Complex (GliSODin) [SOD (Superoxide Dismutase) Enzyme Activity = 500 IU]

500 mg

POMELLA Pomegranate (Punica granatum) Extract (fruit) [std. to 30% punicalagins (120 mg)]

400 mg

Pomegranate (Punica granatum) 5:1 Extract (fruit)

100 mg

PomComplete Pomegranate (Punica granatum) Blend [flower extract and seed oil (standardized to 22% (30 mg) punicic acid)]

137.5 mg

Other ingredients: soybean oil, maltodextrin, gelatin, glycerin, purified water, caramel color, beeswax, phosphatidylcholine.

Contains soybeans and wheat. Contains gluten.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), tree nuts, yeast, corn or rice. Contains NO artificial sweeteners, flavors, colors, or preservatives.

POMELLA Extract is covered under U.S. Patent 7,638,640 and POMELLA is a registered trademark of Verdure Sciences, Inc.
Isocell SA, France is the owner of US Patents Nos. 6,045,809 and 6,426,068B1 and trademark of GliSODin.

Dosage and Use:
 

Take two softgels daily before breakfast, or as recommended by a healthcare practitioner.

 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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