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Life Extension Integra-Lean Irvingia, 150mg, 60 Vcaps

Scientists have identified specific biological mechanisms that cause aging people to gain weight… no matter how little they eat. The problem was that there was no way to circumvent the underlying factors that cause excess body fat… until now! As you are about to learn, gaining control over your body’s command signals is critical to maintaining a healthy weight.

Leptin is a hormone that tells our brain that we have consumed enough calories and can stop eating. Leptin also induces a process whereby fat stored in cells is broken down. As we age, our cells (including the appetite control center in our brains) become “leptin resistant.” This means that leptin is unable to effectively regulate body weight.

Adult-onset weight gain is characterized by the enlargement of existing adipocytes (fat cells) that store too much fat. The size of fat cells is controlled by gene transcription factors.

Fat cell size is closely related with adiponectin expression — with reduced adiponectin expression in larger fat cells. In addition, gene transcription factors help regulate adiponectin, and this crucial hormone is critical for supporting insulin sensitivity.

An enzyme called glycerol-phosphatedehydrogenase is critical for synthesizing fatty acids in our bodies. Suppressing this enzyme helps reduce the amount of glucose (sugar) in our bloodstream from being converted into fatty acids.

Irvingia and Weight Loss Supplements:

Weight loss utilizing diet modification, supplements, hormones or drugs usually functions via a single mechanism. Adipocytes (fat cells), on the other hand, possess numerous means to ensure their survival.

An extract from a West African plant called Irvingia has been shown to help maintain healthy body weight in four ways:

Weight Management -  Reversing Leptin Resistance:

Fat cells produce C-reactive protein, a pro-inflammatory compound that leads to “leptin resistance.” Overweight people given Irvingia have lower levels of CRP, and therefore less CRP is able to block the activity of leptin.

Leptin is important in weight management because it promotes the breakdown of fat in adipocytes and tells the brain to turn off chronic hunger messages.

Hormones -  Increasing Adiponectin:

Large fat cells secrete less adiponectin, and adiponectin is a crucial hormone that helps support insulin sensitivity as well as cardiovascular health. Overweight people given Irvingia show markedly increased adiponectin levels.

Weight Loss -  Inhibiting the Fat Converting Enzyme:

An enzyme called glycerol-phosphate dehydrogenase facilitates the conversion of glucose into triglycerides that increase adipocyte size. Irvingia inhibits glycerol-phosphate dehydrogenase, thus reducing the amount of glucose (sugar) that is converted to fat in the body.

Diet -  Reducing Carbohydrate Absorption:

In order for carbohydrates to be fully absorbed, they must be broken down in the digestive tract by the amylase enzyme. Irvingia inhibits amylase, and thus reduces the amount of ingested starches that will be absorbed as sugar.

Several studies demonstrate the weight loss properties of Irvingia. In the largest placebo controlled human study, those taking Irvingia lost 28 pounds over a 10-week period compared to only up to 3 pounds in the placebo group. The study participants did not alter their diet.

Based on impressive human data, a dose of 150 mg of Integra-Lean Irvingia taken twice a day is all that was needed to achieve unprecedented clinical results.

This supplement should be taken in conjunction with a healthy diet and regular exercise program. Results may vary.

Life Extension's mission is simply to help you live a healthier, longer life. They are at the forefront of medical research, constantly looking for ways to prolong youth, health, and life. They have been at it for more than 34 years, investing more than $140 million to find therapies and technologies that could lead to lifesaving cures for the diseases of aging.

Life Extension insists on purchasing only the highest quality raw materials from all over the world, primarily from leading US, Japanese and European sources. They go one step further by using advanced analytical methods, such as high-performance liquid chromatography and gas chromatography/mass spectrometry, to ensure Their products meet label claims for potency and purity. Life Extension tests its raw materials using US Pharmacopeia and other exacting pharmaceutical assay standard.

Supplement Facts:

Serving Size: 1 capsule

Servings Per Container: 60

Amount Per Serving:

Integra-Lean Irvingia gabonensis proprietary extract (seed)

150 mg

Other ingredients: rice flour, stearic acid, silica,
magnesium stearate, maltodextrin, vegetable cellulose

Contains tree nuts. Contains corn and rice. This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, wheat, yeast, or gluten. Contains NO artificial sweeteners, flavors, colors, or preservatives.

Dosage and Use:

Take one capsule twice daily with or without food, or as recommended by a healthcare practitioner.




Average Rating:
(based on 1 review)

Showing 1 Review:

by Debbie H
on 5/28/2009
from las vegas
I have used this product for 2 months now, and have lost 4 pounds!  I have not done anthing different except take this supplement.  My clothes fit me looser now, it feels good.  It has been a long time since I have been to lose pounds.
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