NOW CurcuBrain, 400 mg, 50 V Capsules

NOW CurcuBrain, 400 mg, 50 VCaps

• Longvida Optimized Curcumin
• Crosses Blood-Brain Barrier
• Free Form Curcumin with Superior Bioavailability
• Vegetarian/Vegan
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Curcumin is a powerful free radical neutralizer that is known to support balanced immune function, but is also known to have poor bioavailability. NOW CurcuBrain features Longvida Optimized Curcumin, which in studies exhibits up to 65 times the bioavailability of free curcuminoids compared with generic curcumin. Longvida is absorbed by the GI tract and delivered to the rest of the body as free curcumin, the active form in the body. Longvida is shown to penetrate the blood-brain barrier for the support of healthy neuronal tissues.

Curcuminoid polyphenols are the primary antioxidant in turmeric root. Curcumin is the principle curcuminoid, and it is responsible for the majority of health benefits attributed to turmeric. The other curcuminoids include desmethoxycurcumin and bis-desmethoxycurcumin.

Blood sugar imbalances and insulin resistance are huge factors that promote inflammatory conditions in the body. Elevated blood sugar creates hazardous glucose cross-links with proteins, causing Advanced Glycolytic Enzymes (AGEs) to form. These AGEs damage cell membranes, vital enzyme systems and perpetuate inflammatory conditions throughout the body.

Curcumin modulates blood sugar and improves insulin receptor function by improving its binding capacity to sugar. Curcumin activates PPAR (peroxisome proliferator-activator receptor), which is a group of key nuclear proteins that regulate gene expression and modulate sugar uptake and utilization in the bloodstream.
Curcumin also reduces the activity of specific liver enzymes that release sugar into the bloodstream while activating enzymes that store sugar as glycogen. Research on diabetic rats resulted in blood glucose stabilization and lowered triglyceride levels in the group that consumed curcumin.

Curcumin also reduces the activity of liver enzymes that release sugar into the bloodstream while activating enzymes that store sugar as glycogen. Research on diabetic rats resulted in blood glucose stabilization and lowered triglyceride levels in the group that consumed curcumin.Turmeric is the fourth most antioxidant-rich herb with an ORACof 159,277. The curcuminoids boost levels of the body's most potent antioxidants including glutathione, superoxide dismutase and catalase. These molecules are critical for the body to limit oxidative stress-related damage to the important organ systems.

Curcumin has been shown to reduce inflammation-mediating prostaglandins, cytokines and other molecules such as interleukin 6, nuclear factor-kappa beta (NF-kb) and tumor necrosis factor-alpha (TNF-alpha). With a high enough dosage, this has the ability to pull the body out of a strong inflammatory cascade and reset anti-inflammatory behavior at the cellular level.

Research done by the Life Extension Foundation found that curcuminoids target ten factors involved in cancer development. This includes chronic inflammation, DNA damage and disruption of cell signaling pathways. Curcumin supplementation was shown to destroy cancer cell mitochondria, disrupt the cancer cell cycle and halt stem cell development that facilitates cancer cell formation.

There are hundreds of other studies that have shown that curcumin turns on naturalcell suicide switches in cancer cells. They also reduce inflammatory prostaglandins that promote cancergrowth. A study out of China showed that curcumin was able to induce apoptosis within triple negative breast cancer cells. TNBC is a type of cancer that defies conventional chemotherapy and radiation, and is very difficult to treat.

Suggested Usage:

As a dietary supplement, take 1 capsule daily.

Not manufactured with yeast, wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only. Consult physician if pregnant/nursing, taking medication, or have a medical condition (including liver dysfunction, gall bladder or gastrointestinal problems). Keep out of reach of children.