Ginkgo biloba extract is a potent antioxidant and scavenger of most free radical species, such as hydroxyl and peroxyl radicals and superoxide anions. It is known to protect the energy–producing mitochondria within the cells, thus enhancing oxygen utilization and cellular respiration.
In a study to determine whether ginkgo extract could prevent age-associated cellular changes, the brain and liver mitochondria of old mice fed ginkgo extract in their drinking water was compared to those of young and old control mice.
Mitochondria from the rats given ginkgo exhibited significantly less genetic damage, peroxide generation, and oxidation of the crucial antioxidant glutathione than the nonsupplemented rats.
In addition, mitochondria from the old rats given the ginkgo extract resembled those of the young rats much more closely, being similar in size and morphology. The study concluded that standardized ginkgo extract prevents age-related decline in mitochondrial structure and function by protecting mitochondria from oxidative damage.
The pharmaceutical grade botanical extract in Ginkgo Biloba Certified Extract has been concentrated and dual standardized to ensure the highest quality, consistency, and biological activity.
Ginkgo Biloba Certified Extract contains the lowest level of ginkgolic acid available, even lower than the stringent 5 ppm German Commission E limit. Ginkgolic acid is an allergen for some people and is present in much higher levels in lower quality products.
Ginkgo Biloba Certified Extract has high levels of ginkgolide B (>0.8%), which is the most studied terpene lactone, and thought to be a potent inhibitor of platelet activating factor (PAF). PAF is a powerful inflammatory mediator.
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